Course: Pharmacology and Pharmacy I

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Course title Pharmacology and Pharmacy I
Course code 1500/VAFA1
Organizational form of instruction Lecture + Tutorial
Level of course Master
Year of study not specified
Semester Summer
Number of ECTS credits 4
Language of instruction English
Status of course unspecified
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Course availability The course is available to visiting students
Lecturer(s)
  • Tomiczkova Zuzana, MVDr.
  • Chloupek Jan, MVDr. Ph.D.
  • Kramářová Eva, RNDr. Ph.D.
Course content
LECTURES 1) Introduction to pharmacology and definition of basic terms. National and European pharmaceutical legislation and its basics related to the food chain and environmental protection 2) Drug prescription and distribution and proper choice of a medicinal product in accordance with current legislation 3) Pharmacokinetics. Drug resorption, distribution, biotransformation and elimination. Pharmacokinetics in different species with a focus on livestock and its products 4) Drug effects. Dosology. The ways of drug administration and its effects on the protection of the food chain and the environment 5) Pharmacodynamics. Drug specific and unspecific mechanisms of action. Drug-receptor interaction, agonism and antagonism. Types of cellular receptors, ways of signal transduction. Examples of the pharmacological effects on the receptors in various tissues with the main focus on livestock 6) Evaluation of the quality, efficacy and safety of the drugs with an emphasis on ensuring the protection of the food chain and the environment. Minimal residual limits (MRL). Withdrawal periods 7) Principles of handling addictive substances. National legislation on addictive substances and their specificities in livestock 8) Pharmacovigilance and adverse effects of drugs. Pharmacovigilance and the protection of the food chain and environment PRACTICALS 1) Introduction, definitions of basic terms in pharmacology. Overview of the Latin terminology and essential vocabulary used for a veterinary prescription 2) Introduction to veterinary drugs prescription. Prescription of individually prepared medicines. Introduction to the dosage forms 3) Solid, semisolid and liquid external dosage forms with emphasis on veterinary practice 4) Pharmacopoeia. Drug labelling 5) Dosage forms administered into accessible body cavities with an emphasis on veterinary practice. Prescribing using the term quantum satis 6) Prescribing ready-made preparations. Available resources of information about veterinary and human medicines 7) Dosology, concentration and dose calculations. TEST 8) Parenteral dosage forms with emphasis on veterinary practice. Prescription of autogenous vaccines 9) Solid, semisolid and liquid peroral dosage forms with emphasis on veterinary practice. Prescription of medicated feed 10) Psychoactive drugs - legislation, obligatory records and disposal. Annual report on production, usage, disposal and trading of medicines containing addictive substances. Techniques of distance immobilization of animals and principles of handling related anaesthetic drugs 11) Dermatologics. Human and veterinary medicine technical equipment 12) Distribution of veterinary medicines. Trip to the distribution company - Covetrus 13) Disinfectants. TEST 14) Drug records. Principles of drug storage. Practising veterinary prescription

Learning activities and teaching methods
Lectures, Seminars, Professional excursion
Learning outcomes
The first semester is focused on basic principles of general pharmacology. The main part of the theoretical preparation is acquiring essential knowledge in pharmacokinetics and pharmacodynamics. Following with evaluation of the quality, efficacy and safety of the drugs, lectures are focused on the adverse effects of the drugs and their surveillance (pharmacovigilance). Practicals are focused on veterinary prescription, dosology and dosage forms, distribution and storage of the drugs and related drug records
Theoretical knowledge - The student is able to describe the basic principles of pharmacokinetics and pharmacodynamics with respect to the differences between various animal species and the specifics of the use of various dosage forms. Practical skills - The student can recognize situations related to pharmacological surveillance (pharmacovigilance) and suggest how to proceed in such situations. - The student is able to perform and keep records and documentation of the use of drugs, including narcotics and psychotropic substances and precursors. Competences - Based on theoretical knowledge of legal regulations, the student is competent to use medicines responsibly. - The student is able to work with the resources of information on the range of drugs and registered medicinal veterinary and human products. - The student is competent to prescribe, order and dispense individually and ready-made medicinal products according to current legislation and to determine the therapeutic dose of drugs in individual species and categories of animals.
Prerequisites
unspecified

Assessment methods and criteria
unspecified
Requirements for obtaining credits: 1. Active attendance at the practicals 2. Completing assigned tasks and case studies in the area of distribution and storage of drugs and drug records 3. Active knowledge of the current topics of lectures and practicals 4. Successful completion of the tests throughout the semester
Recommended literature
  • Aiello, S., E. and others. The Merck Veterinary Manual. Whitehouse Station, N.J., USA, 1998.
  • Bishop, Y. (ed). The Veterinary Formulary, 6th Edition. Pharmaceutical Press, London, 2004.
  • Donald C. Ahrens, Franklin A. Ahrens. Pharmacology, Edition Due. Blackwell Publishers, 1996.
  • H. Richard Adams. Veterinary Pharmacology and Therapeutics, 8th Edition. Iowa State University Press, 2001.
  • Hadašová E. et al. Practicals in pharmacology. Faculty of Medicine, Masaryk University, Brno, 2006.
  • Hsu, W.H. Handbook of Veterinary Pharmacology. Wiley-Blackwell, Iowa, 2008.
  • Kahn, C.M. Line, S.(eds.). The Merck Veterinary Manual, 9th Edition. Merck/CO., U.S.A., 2005.
  • Katzung, B.G. Basic/Clinical Pharmacology.. Norwald, CT., 1992.
  • Kayne, S.B., Jepson, M.H. (eds.). The Veterinary Pharmacy. Pharmaceutical Press, London, 2004.
  • Lincová, D. a kol. Základní a aplikovaná farmakologie. Galén Praha, 2002.
  • Lüllmann H. et. al. Color Atlas of Pharmacology, 3rd Edition. Thieme Medical Publishers, 2005.
  • Maddison, J. E. et al. Small Animal Clinical Pharmacology. London, Saunders, 2008.
  • Rang H.P. et al. Rang/Dale´s Pharmacology, 6th Edition. Churchill Livingstone, 2007.
  • Riviere, J.E. et al. Veterinary Pharmacology and Therapeutics, 9th Edition. Wiley-Blackwell, 2009.
  • Steven B Kayne, Michael H Jepson. The Veterinary Pharmacy. Pharmaceutical Press, London, 2004.
  • Šimůnek, J., Smola, J.;. Antimikrobiální léčiva ve Veterinární medicíně. 2007.
  • Šnirc, J., Sokol, J., Seginko, J., Hera, A. Klinická veterinárna farmakológia. 2007.
  • Tennant, B.;. BSAVA Small Animal Formulary 4th Edition, BSAVA (British Small Animal Veterinary Association). 2002.
  • Yolande Bishop. The Veterinary Formulary, 6th Edition. Pharmaceutical Press, London, 2004.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester